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Talazoparib isn’t an inhibitor regarding transporters plus P-gp, BCRP, OATP1B1, OATP1B3, OCT1, OCT2, OAT1, OAT3, BSEP, MATE1, and you can MATE2-K

Talazoparib isn’t an inhibitor regarding transporters plus P-gp, BCRP, OATP1B1, OATP1B3, OCT1, OCT2, OAT1, OAT3, BSEP, MATE1, and you can MATE2-K

Customers was in fact needed to have received treatment which have a keen anthracycline and you will/or a beneficial taxane (unless contraindicated) about neoadjuvant, adjuvant, and/otherwise metastatic therapy means

Effectation of acidic-cutting agents to the talazoparib: Coadministration away from acidic-reducing agencies including proton push inhibitors (PPI), histamine receptor dos antagonists (H dos RA), and other acidic reducing representatives has no effect on the brand new consumption away from talazoparib.

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